Senior Bioinformatics Scientist

at Lucigen
Location Middleton, Wisconsin
Date Posted July 9, 2021
Category Bioscience
Job Type Full-time
Address 2905 Parmenter Street

Description

LGC Genomics is looking for a highly analytical and driven individual to join our global R&D team as Senior Bioinformatics Scientist. The individual would play a key role in expanding LGC’s molecular biology product portfolio. The successful candidate will become part of the newly restructured, exciting, and dynamic bioinformatics team that supports multiple divisions within LGC. The ideal candidate would have experience in programming, next generation sequencing (NGS) data analysis, and developing new analysis tools. The primary responsibilities include designing genotyping and diagnostics assays, troubleshooting data analysis problems, and developing pipelines for various PCR and NGS based applications.

 

PRIMARY DUTIES AND RESPONSIBILITIES:

  • Develop oligo design tools and pipelines for molecular techniques such as qPCR and NGS
  • Build pipelines and tools for NGS data analysis and new product development
  • Generate, optimize and maintain scripts for routine genomic data processing, curation, and storage
  • Design high-throughput multiplexing genotyping panels for humans, plants, animals, and microbes
  • Provide customized data analysis, troubleshooting, and training support to the bench scientists and NGS services staff
  • Collaborate with product management, program management, NGS services, and molecular biology teams for new product development and custom NGS projects/services
  • Identify and define new product ideas or technologies; develop prototypes, conduct optimization studies, and present results to the leadership
  • Attend meetings, conferences, symposia, and seminars to promote LGC capabilities and to keep abreast of scientific/technological developments
  • Deliver high-quality product development documentation consistent with LGC’s quality systems
  • Follow company requirements of the ISO 13485 quality management system
  • Other duties as assigned

Qualifications

  • M.S. degree in bioinformatics, computer science, biostatistics, computational biology, genetics, or a related field with at least 5 years’ relevant experience; or Ph.D. degree in a related field with 1-3+ years relevant experience
  • Proficiency in high-level (Python, Perl) and low-level (c, c++) programming languages
  • Experience with LINUX-based operating systems and shell scripting
  • Excellent data analysis and visualization skills (R, matplotlib, or similar)
  • Experience in computational pipeline development and database management, as well as a solid background in genomics and statistics.
  • Deep understanding of NGS algorithms and data analysis tools
  • Excellent understanding of molecular biology and NGS products/methods, platform-specific capabilities, and data interpretation
  • Hands-on experience with analyzing and managing large-scale genomic data (e.g. whole genome sequencing, exome-seq, target enrichment, amplicon sequencing, RNA-seq, etc.)
  • Hands-on experience with genome alignment, mapping, variant calling and annotation tools
  • Familiarity with human, mammalian, plant and microbial genomics, and standard genomic databases (UCSC, ENSEMBL, NCBI), formats, and tools
  • Aptitude for complex problem-solving and continuous improvement, with the willingness to work in a rapidly growing matrix organization
  • Must demonstrate good professional judgment, reliability, and diligence
  • Excellent oral and written communication skills

 

Click here to learn more & apply today!